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The dispersion suitably can be formed by shearing or otherwise mixing a mixture/combination of its components. The dispersions can be used to form nanoparticle composite
Stirred media mills are widely used in industry for fine and ultra-fine grinding of various materials and dispersion of aggregates. There is a growing interest in the large- ... The Kodak patents ... little work has been performed in understanding nanoparticle production through a grinding process.13-15 This study will further the understanding ...
Good control of the size, shape, and dispersion is of great significance for the preparation and application of nanomaterials. In this paper, we report a novel electrospinning–calcination–grinding route to prepare well-dispersed inorganic nanoparticles and …
Dispersion media can be water, aqueous solutions or nonaqueous media (eg, liquid polyethylene glycol [PEG], oils). Depending on the production technology, processing of drug microcrystals to drug nanoparticles can lead to an either crystalline or to an amorphous …
Over the past few years we have observed an increase in the desire to use bead mills for grinding and dispersion of "nanoscale" particles. The objective of this paper is a general discussion of how this process works in a bead mill, the parameters required to successfully produce these nanoscale dispersions, and some experience in grinding or particle size reduction of solids to the nanoscale.
nanoparticle dispersion grinding patent. By grinding micro-sized coarse powder with grinding beads of 50 μm in diameter the mean hydrodynamic diameter of Cs 0.33 WO 3 powder could be reduced to about 50 nm in 3 h and a stable aqueous dispersion could be …
Solid dispersion is a versatile technology used to develop oral solid dosage forms of poorly water-soluble drugs. ... Gordon et al. produced PVA nanofibers with confined amorphous celecoxib nanoparticles by electrospinning PVA in volatile oil ... Kohei Tahara has patent #Japanese Patent Application No.2020-192876 pending to Mitsubishi Chemical ...
US20120056121A1 US13/176,515 US201113176515A US2012056121A1 US 20120056121 A1 US20120056121 A1 US 20120056121A1 US 201113176515 A US201113176515 A US 201113176515A US 2012056121 A1 US2012056121 A1 US 2012056121A1 Authority US United States Prior art keywords nanoparticles magnetite grinding acid ore Prior art date Legal status (The legal status is …
First, it is a water borne dispersion, which precludes any similarity to the first two Xerox quotes that are based on non-polar solvents. In the third Xerox patent, U.S. Pat. No. 8,236,192 B2; all of the magnetic pigment dispersions undergo a process of comminution, by milling or using high shear rate mixers.
The described particles can be prepared in a method comprising the steps of dispersing the R(-) ibuprofen or fenoprofen in a liquid dispersion medium and applying mechanical means in the presence of grinding media to reduce the particle size of the therapeutic or diagnostic agent to an effective average particle size of less than about 400 nm.
What is claimed is: 1. A stable dispersion comprising: a continuous phase comprising a continuous liquid phase and a plurality of excipient surface-modified organic nanoparticles; and a dispersed phase comprising one or more medicament particles dispersed in the continuous phase, wherein the dispersion comprises less than 0.001 percent by weight of surfactant, surface-active agents, detergents ...
In situ production of titanium dioxide nanoparticles in molten salt phase for thermal energy storage and heat-transfer fluid applications ... dissertations and also led to a patent application on a technique of production of in situ nanoparticles and nanofins (Shin and Banerjee 2010; Shin 2011; Shin ... After grinding the mixture for 10–15 ...
Probucol nanoparticles were prepared by co-grinding with various molecular weights of polyvinylpyrrolidone (PVP K12, PVP K17 and PVP K30) and sodium dodecyl sulfate (SDS). ... dispersion into ...
A nanoparticle dispersion of Danazol was prepared for clinical evaluation using a ball milling dispersion method. This dispersion was prepared by milling with glass grinding media. The grinding media used was: Media type: 0.85-1.18 mm unleaded glass spheres . Media quantity: 6100 ml . The media was added to a 3 gallon porcelain jar.
We have discovered stable, dispersible drug nanoparticles and a method for preparing such particles by wet milling in the presence of grinding media in conjunction with a surface modifier. The particles can be formulated into pharmaceutical compositions exhibiting remarkably high …
The wetting and homogenization of solids in liquids, deagglomeration and dispersion, all the way to true comminution of primary particles make the agitator bead mill a universal wet processing machine. Depending on the product properties, various types of agitator …
The major trends in the development of grease products are described in an analysis of the relevant research and patent literature, including research on superalkaline calcium greases for heavilyloaded friction units and possible applications of nanoparticle additives to multifunctional greases. Developments in lowtemperature greases derived from biodegradable polyester bases and lubricants ...
Bonds based on Cu-Ni-Fe-Sn alloy and dispersion-hardened with W, WC, NbC, Al2O3, ZrO2, Si3N4, and BN nanoparticles have been developed for the use in diamond tools designed for cutting reinforced ...
A nanoparticle dispersion of Danazol was prepared for clinical evaluation using a ball milling dispersion method. This dispersion was prepared by milling with glass grinding media. The grinding media used was: Media type: 0.85-1.18 mm unleaded glass spheres. Media quantity: 6100 ml. The media was added to a 3 gallon porcelain jar.
JP-5243510-B2 chemical patent summary.
Chitosan-supported gold nanoparticles (NPs) with excellent control of size and shape were rapidly synthesized in gram-scale by solid-grinding without the need of any toxic solvents. The structure of catalysts and products was established by advanced instrumental and spectroscopic methods.
To sum up, among the drug nanoparticle technologies available, bead milling offers a convenient process for production of nanoparticle dispersion at high concentrations for solid dosage form processing that offers ease of scale-up to enable commercial manufacturing. The pros and cons of nanoparticle technologies are summarized in Table 3 .
US-2014329067-A1 chemical patent summary. Dispersion comprising metallic, metal oxide or metal precursor nanoparticles, a polymeric dispersant and a sintering additive
An object of the present invention is to provide a semiconductor nanoparticle exhibiting excellent air durability, a semiconductor nanoparticle-containing dispersion liquid containing the semiconductor nanoparticle, and a film containing the semiconductor nanoparticle. In the semiconductor nanoparticle of the present invention, zinc, sulfur, and indium are detected by energy …
In fact, the interface here between polymer matrix and nanoparticle plays a significant role in this. The nanoparticles dispersion is the key challenge to achieve improved properties, such as flame retardance, mechanical, barrier, and thermal properties. ... grinding, calendaring, blow molding, compression molding ... Recent Patents Nanotechnol ...
US9669375B2 - Method for production of stable cerium oxide organic colloids - Google Patents An improved process for producing substantially non-polar doped or un-doped cerium oxide nanoparticle...
Based on a commercial zeolite of the MFI type, nanoparticles have been produced using mechanical methods (grinding in a ball or planetary mill, classification by "stirring-up") and ultrasonic treatment (UST) of zeolite in water. It has been found by spectral methods (XRD, DRIRS, 27Al and 29Si solid-state NMR) and adsorption analysis that the grinding of the zeolite leads to partial ...
Media milling: Nanocrystal is a patent protected technology developed by Liversidge et al. In this technique, the drug nanoparticles are obtained by subjecting the drug to media milling. High energy and shear forces generated as a result of impaction of the milling media with the drug
Results show that, in the experimental pressure range (5.5 to 20 MPa), the pressure has no significant effect on the dispersion of nanoparticles, and the cosolvent is the key factor in dispersing ...
- Google Patents The present invention relates to a nano-diamond dispersion solution and a method of preparing the same.
Nanoparticle coatings for flexible and/or drawable substrates US7438972 Flexible and/or drawable substrates having coatings comprising a dispersion of resin coated nanoparticles are disclosed, as are laminated articles comprising such flexible and/or drawable substrates .
Nanoparticles (NPs) of naproxen (a nonsteroidal anti-inflammatory drug, BCS Class 2) and sesamin (a poorly water-soluble lignan) were investigated. By applying a newly developed rapid expansion system of liquid carbon dioxide solutions equipped with a dielectric nozzle, well-separated and fine both naproxen NPs (averaged particle size (APS) = 46.9 nm) and sesamin NPs (APS = 60.2 nm) …
The traits of lipid biocompatibility and versatility have led to many nano- and microparticulate lipid formulations being engineered, over the last two decades, in the form of spheres and capsules, using solid and liquid lipids as the matrices. This review describes the main types of lipid nano- and microparticles, as well as their preparation methods, administration routes, and main fields of ...
Nanoparticle jet MQL grinding has all the advantages of MQL grinding while also enhancing heat exchange in the grinding zone to evidently improve workpiece surface quality and burn situation (Zhang et al., 2012a, Zhang et al., 2012b). The technology also prolongs the service life of the grinding wheel and improves the working environment.
The dispersion of ferroelectric nanomaterials in liquid crystals has recently emerged as a promising way for the design of advanced and tunable electro-optical materials. The goal of this paper is a broad overview of the current technology, basic physical properties, and applications of ferroelectric nanoparticle/liquid crystal colloids. By compiling a great variety of experimental data and ...
A process to prepare a stable dispersion of nanoparticles in aqueous media. A dispersant and aqueous are combined to form a mixture. The dispersant is selected from the group comprising copolymers and cyclic phosphates. Nanoparticles are added to the mixture to form the dispersion.
Electrolytic plating compositions and electrolytic plating processes for the co-deposition of silver or silver alloy with fluoropolymer nanoparticles are provided. The silver or silver alloy composite coating containing fluoropolymer nanoparticles has enhanced functional properties such as a reduced coefficient of friction. The electrolytic plating composition comprises: (a) a silver ion ...
Grinding and Dispersing Nanoparticles 54 January 2004 JCT CoatingsTech O ver the past few years we have observed an increase in the de-sire to use bead mills for grinding and dispersion of "nanoscale" parti-cles. The objective of this paper is a general discussion of how this process works in a bead mill, the parameters required to successfully
Nanoparticles must be first dispersed in a liquid to be used effectively, and over the past few years, the use of fine bead mills for grinding and dispersion of these particles has become more and more prevalent. Fine bead mills, widely used in both laboratory and production applications, deliver an efficient
activity. Nanoparticles are used to render printing substrates suitable for photo-quality ink-jet printing. The particle dispersion can only be applied if the viscosity of the coating composition is low. In all these cases, the dispersion process including chemical modification is the key element.
